Please check this article ( How to enable Skype features in your ASP.NET website
Also a discussion here
But as Siva Prasad said
But you can integrate twitter and facebook in your asp.net web application. Your application call a special API provide by the platform (Facebook or Twitter), user has to enter their credentials in the UI. This UI is provided by the the platform and not controlled by my application. The platform after validating the user information will return a token to my application. This token is what I store and relate it to this particular user. Now when you call, let say an API to post content you have to provide the token. The platform verifies that the token is valid and then it will post the content to the appropriate account that is related to the token you provided.
Hemanth.Gottipati, if this helps please login to Mark As Answer. | Alert Moderator