I haven�t seen a whole of of issues around this as of yet, but now that 3.5 SP1 has released that may change. If you copy SOS.dll to another location and then load it out of that directory to troubleshoot dumps, you may start seeing problems. Namely, things like !clrstack not returning any valid names for functions and just printing out the numbers. For example:
0:006> !clrstack
OS Thread Id: 0x1154 (6)
ESP EIP
0154cfdc 7614f35f [HelperMethodFrame: 0154cfdc]
0154d080 5fb7b8cd
0154d094 5fb7b78b
0154d0bc 5fd26907
0154d0d0 5f95a87c
0154d0e8 5f959458
0154d108 5f9634f1
0154d124 5f96342d
0154d150 65525e55
0154d17c 5e339ea3
0154d1f8 5e33ce4d
0154d37c 5e3400cc
0154d380 5dd60d14
0154d3b4 5e56def3
0154d408 5dce876b
0154d438 5dd12799
0154d47c 5dd0df51
0154d4b0 5dcea92a
0154d714 6e871b4c [GCFrame: 0154d714]
0154d730 6e871b4c [GCFrame: 0154d730]
0154d8a4 6e871b4c [ContextTransitionFrame: 0154d8a4]
...
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