Calling webservice from javascript

        <asp:ScriptManager ID="ScriptManager1" runat="server" LoadScriptsBeforeUI="False">        
            <Scripts>
                <asp:ScriptReference Path="myscript.js" />
            </Scripts>
            <Services>
                <asp:ServiceReference Path="MyService.asmx" />
            </Services>
        </asp:ScriptManager> 
i want to call the web service MySe ...