How to easily empty/null out asp Profile state?

I'm using profiles to save control settings of users.
I have a check box that enables them to 'enable' saving their settings.
 
rather than cycling through each parameter, and setting them to Null,
is there a way  I can do something like:
Profile.Something = Null

http://msdn.microsoft.com/en-us/library/2y3fs9xs.aspx
 
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